BDBM50355177 CHEMBL1835712

SMILES Cc1nc2ccc(cn2n1)-c1cn(nc1-c1cccc(C)n1)C(=S)Nc1cccc(c1)C#N

InChI Key InChIKey=AJKCRAIFDAOTLV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50355177   

TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50355177(CHEMBL1835712)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50355177(CHEMBL1835712)
Affinity DataIC50: 85.3nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed