BDBM50354923 CHEMBL1836881

SMILES Nc1nc(cc2n(Cc3ccc(nc3)N3CCC[C@H]3CN3CCCC3)c(=O)[nH]c12)C(F)(F)F

InChI Key InChIKey=KSLHGCDGNLJGCD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354923   

TargetToll-like receptor 7(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354923(CHEMBL1836881)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at TLR7 in human PBMC assessed as induction of type 1 interferon productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed