BDBM50354699 CHEMBL1834184

SMILES CCC(=O)N[C@H]1CC[C@H](C1)C(=O)N(C)c1ccc(cc1)-c1nc2ccccc2o1

InChI Key InChIKey=YNFDIGJKJPNFFD-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50354699   

TargetFatty acid synthase(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50354699(CHEMBL1834184)
Affinity DataIC50: 79nMAssay Description:Inhibition of human FAS assessed as synthesis of long chain fatty acids from malonyl CoA after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetFatty acid synthase(Mouse)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50354699(CHEMBL1834184)
Affinity DataIC50: 600nMAssay Description:Inhibition of FAS in mouse N42 cells assessed as [14C]-acetate incorporation after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50354699(CHEMBL1834184)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50354699(CHEMBL1834184)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50354699(CHEMBL1834184)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50354699(CHEMBL1834184)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50354699(CHEMBL1834184)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed