BDBM50354525 CHEMBL411663

SMILES Fc1ccc2NC(=O)C(CCCCN3CCN(CC3)c3ccccc3)c2c1

InChI Key InChIKey=IBBIDLLHDNJIPV-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50354525   

TargetAlpha-1A adrenergic receptor(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354525(CHEMBL411663)
Affinity DataKi:  20nMAssay Description:Inhibition of adrenergic alpha-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354525(CHEMBL411663)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354525(CHEMBL411663)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]CT from human 5-HT7 receptor expressed in CHO cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354525(CHEMBL411663)
Affinity DataKi:  55nMAssay Description:Inhibition of 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354525(CHEMBL411663)
Affinity DataKi:  150nMAssay Description:Inhibition of 5HT1A receptor in rat frontal cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354525(CHEMBL411663)
Affinity DataKi:  154nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor in rat frontal cortex membrane after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354525(CHEMBL411663)
Affinity DataKi:  330nMAssay Description:Inhibition of dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354525(CHEMBL411663)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354525(CHEMBL411663)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354525(CHEMBL411663)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed