BDBM50354279 CHEMBL1836603

SMILES Cc1ccc(cc1)[C@H]2c3cc(ccc3N=C(N2CCCN(C)C)C)Cl

InChI Key InChIKey=RZVYHDCYMAMDJY-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50354279   

TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50354279(CHEMBL1836603)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant trypanothione reductase from Trypanosoma brucei brucei S427 by DTNB-coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50354279(CHEMBL1836603)
Affinity DataKi:  190nMAssay Description:Competitive inhibition of recombinant trypanothione reductase from Trypanosoma brucei brucei S427 by Lineweaver burk methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50354279(CHEMBL1836603)
Affinity DataKi:  1.46E+3nMAssay Description:Mixed type inhibition of recombinant trypanothione reductase from Trypanosoma brucei brucei S427 by Lineweaver burk methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)