BDBM50354246 CHEMBL1836461

SMILES COc1cccc(CSc2nc(SCc3ccccc3)nc(=O)[nH]2)c1

InChI Key InChIKey=KDISDFRLUVJJGD-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50354246   

TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50354246(CHEMBL1836461)
Affinity DataIC50: 4.85E+5nMAssay Description:Inhibition of human DNA topoisomerase IIalpha using plasmid pNO1 as a substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50354246(CHEMBL1836461)
Affinity DataKi:  1.30E+4nMAssay Description:Reversible inhibition of human recombinant cathepsin B assessed as formation of fluorescent degradation product AMC using Z-Arg-Arg-AMC as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50354246(CHEMBL1836461)
Affinity DataKi:  2.19E+4nMAssay Description:Partial mixed-type inhibition of human recombinant cathepsin B assessed as formation of fluorescent degradation product AMC using Z-Arg-Arg-AMC as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed