BDBM50354023 CHEMBL1830519

SMILES CCCN(CCC)c1c(C)c(Nc2ccc(OC)cc2Cl)nc2nccn12

InChI Key InChIKey=REMGRHFBTRPVEO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50354023   

TargetCorticotropin-releasing factor receptor 1(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50354023(CHEMBL1830519)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50354023(CHEMBL1830519)
Affinity DataEC50:  46nMAssay Description:Antagonist activity at human CRF1 receptor expressed in CHO-K1 cells assessed as inhibition of CRF-induced cAMP accumulation after 15 mins by cAMP en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed