BDBM50354015 CHEMBL1828900

SMILES CCCN(CCC)c1cc(nc2ccnn12)N(CC=C)c1ccc(OC)cc1Cl

InChI Key InChIKey=KPHGNPJLAYZDKV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50354015   

TargetCorticotropin-releasing factor receptor 1(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50354015(CHEMBL1828900)
Affinity DataIC50: 4.40nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50354015(CHEMBL1828900)
Affinity DataEC50:  28.9nMAssay Description:Antagonist activity at human CRF1 receptor expressed in CHO-K1 cells assessed as inhibition of CRF-induced cAMP accumulation after 15 mins by cAMP en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed