BDBM50353443 CHEMBL1829863::US10196373, Compound 45D

SMILES CN(CC(=O)N(Cc1ccc(cc1)C1CCCCC1)c1ccc(C(O)=O)c(O)c1)S(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=CCICSAGMQVXOBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50353443   

TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353443(CHEMBL1829863 | US10196373, Compound 45D)
Affinity DataIC50: 7.92E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
The Governing Council of The University of Toronto

US Patent
LigandPNGBDBM50353443(CHEMBL1829863 | US10196373, Compound 45D)
Affinity DataIC50: 7.92E+4nMAssay Description:ChIP assay was performed using EZ ChIP Kit (Millipore, Billerica, Mass., USA) as per manufacturer's instruction. Briefly, after crosslinking with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
Go to US Patent