BDBM50353337 CHEMBL1831057

SMILES Cn1c2c3C(Nc4ccccc4-n3c(-c3ccccc3)c2c(=O)n(C)c1=O)c1ccc(Cl)o1

InChI Key InChIKey=AQALXPHLZZZACW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353337   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50353337(CHEMBL1831057)
Affinity DataIC50: 150nMAssay Description:Inhibition of human wild-type CFTR expressed in FRT cells coexpressing YFP-H148Q assessed as inhibition of cAMP agonist-induced iodide influx after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed