BDBM50353290 CHEMBL1830707

SMILES C1Cc2[nH]ncc2-c2nc(Nc3ccccn3)sc2C1

InChI Key InChIKey=DBISXWCOHGUFSF-UHFFFAOYSA-N

Data  6 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50353290   

TargetMetabotropic glutamate receptor 3(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353290(CHEMBL1830707)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu3 receptor assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353290(CHEMBL1830707)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of mGlu5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353290(CHEMBL1830707)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of mGlu2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353290(CHEMBL1830707)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of mGlu1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353290(CHEMBL1830707)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu7 receptor assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353290(CHEMBL1830707)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu2 receptor assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353290(CHEMBL1830707)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu5 receptor assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353290(CHEMBL1830707)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of mGlu7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353290(CHEMBL1830707)
Affinity DataEC50:  9nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353290(CHEMBL1830707)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu1 receptor assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353290(CHEMBL1830707)
Affinity DataIC50: 1.00E+4nMAssay Description:Positive allosteric modulation of mGlu3 receptor assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50353290(CHEMBL1830707)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed