BDBM50353040 CHEMBL1822519

SMILES COc1ccccc1-c1ccc2cnc(Nc3ccc(cc3OC)N3CCN(C)CC3)nn12

InChI Key InChIKey=OUCKZVRLUAQTBL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50353040   

TargetALK tyrosine kinase receptor/Nucleophosmin(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353040(CHEMBL1822519)
Affinity DataIC50: 100nMAssay Description:Inhibition of NPM/ALK phosphorylation in human KARPAS299 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353040(CHEMBL1822519)
Affinity DataIC50: 391nMAssay Description:Inhibition of IRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353040(CHEMBL1822519)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant ALK assessed as phosphorylated product using PLC-gamma/GST substrate by modified ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed