BDBM50353003 CHEMBL1825183

SMILES Cc1c(F)cccc1Cc1c(C(=O)N2CCNCC2)c2ccncc2n1-c1ccccc1

InChI Key InChIKey=SBBODXSOBKNATM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50353003   

TargetRenin(Human)
Deutschland

Curated by ChEMBL
LigandPNGBDBM50353003(CHEMBL1825183)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant renin using dabcyl-gamma-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS as substrate preincubated for 30 mins afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetRenin(Human)
Deutschland

Curated by ChEMBL
LigandPNGBDBM50353003(CHEMBL1825183)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant renin using dabcyl-gamma-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS as substrate preincubated for 30 mins afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetRenin(Human)
Deutschland

Curated by ChEMBL
LigandPNGBDBM50353003(CHEMBL1825183)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant renin using dabcyl-gamma-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS as substrate preincubated for 30 mins afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed