BDBM50352894 CHEMBL1824626

SMILES Cc1ccc(F)cc1Oc1c(C(=O)N2CCNCC2)c2cc(O)cnc2n1-c1ccccc1

InChI Key InChIKey=USWPHVRQAASSRK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50352894   

TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50352894(CHEMBL1824626)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human renin using Dabcyl-gamma-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS as substrate preincubated for 30 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50352894(CHEMBL1824626)
Affinity DataIC50: 189nMAssay Description:Inhibition of recombinant human renin using Dabcyl-gamma-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS as substrate preincubated for 30 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50352894(CHEMBL1824626)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human renin using Dabcyl-gamma-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS as substrate after 2 hrs by spectrofluorom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed