BDBM50352809 CHEMBL458094

SMILES [#6]-[#8]-c1ccc(-[#6](=O)\[#6]=[#6]\c2ccc(-[#8])cc2)c(-[#8])c1-[#6]\[#6]=[#6](\[#6])-[#6]

InChI Key InChIKey=NJYUIKQYURZCCZ-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50352809   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50352809(CHEMBL458094)
Affinity DataIC50: 7.29E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Brevig Mission/1/1918 ...)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50352809(CHEMBL458094)
Affinity DataIC50: 4.21E+4nMAssay Description:Inhibition of Influenza A virus (A/Brevig Mission/1/1918(H1N1)) recombinant neuraminidase using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50352809(CHEMBL458094)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human MAO-A using kynuramine as substrate incubated for 20 mins by fluorescence based assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50352809(CHEMBL458094)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of human MAO-B using kynuramine as substrate incubated for 20 mins by fluorescence based assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Brevig Mission/1/1918 ...)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50352809(CHEMBL458094)
Affinity DataKi:  5.02E+4nMAssay Description:Noncompetitive inhibition of Influenza A virus (A/Brevig Mission/1/1918(H1N1)) recombinant neuraminidase using 4-methylumbelliferyl-alpha-D-N-acetyln...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed