BDBM50352763 CHEMBL1823222

SMILES CCCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC1)C1COC1

InChI Key InChIKey=OUQRQZVDADPPCN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50352763   

TargetALK tyrosine kinase receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352763(CHEMBL1823222)
Affinity DataIC50: 15nMAssay Description:Inhibition of ALK activity by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352763(CHEMBL1823222)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MET activity by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352763(CHEMBL1823222)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of KDR activity by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352763(CHEMBL1823222)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of KIT activity by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed