BDBM50352748 CHEMBL1822904::US8835436, Example 10

SMILES COc1ccc(cc1)-n1c(C)nc(C(=O)NCCCN2CCN(CC2)c2cccc(Cl)c2Cl)c1C

InChI Key InChIKey=KLFKNFRLZJDZER-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50352748   

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

US Patent
LigandPNGBDBM50352748(CHEMBL1822904 | US8835436, Example 10)
Affinity DataIC50: 20nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

US Patent
LigandPNGBDBM50352748(CHEMBL1822904 | US8835436, Example 10)
Affinity DataIC50: 88nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

US Patent
LigandPNGBDBM50352748(CHEMBL1822904 | US8835436, Example 10)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]ketanserin from human recombinant serotonin 5-HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

US Patent
LigandPNGBDBM50352748(CHEMBL1822904 | US8835436, Example 10)
Affinity DataIC50: 88nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352748(CHEMBL1822904 | US8835436, Example 10)
Affinity DataIC50: 33nMAssay Description:Displacement of [3H]impiramine from human serotonin transporter membrane expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed