BDBM50352702 CHEMBL1823067

SMILES Cc1c(Cl)cccc1N1CCN(CCCNC(=O)c2nc(-c3ccccc3)n(c2Cn2cncn2)-c2ccccc2)CC1

InChI Key InChIKey=YMAOGAGJBIXOCM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50352702   

TargetCytochrome P450 2D6(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352702(CHEMBL1823067)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human recombinant CYP2D6 by luceferin-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352702(CHEMBL1823067)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 by luceferin-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50352702(CHEMBL1823067)
Affinity DataIC50: 9.80E+3nMAssay Description:Displacement of [3H]astemizole from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352702(CHEMBL1823067)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of human recombinant CYP1A2 by luceferin-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352702(CHEMBL1823067)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human recombinant CYP2C9 by luceferin-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352702(CHEMBL1823067)
Affinity DataIC50: 12.3nMAssay Description:Displacement of [3H]ketanserin from human recombinant serotonin 5-HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352702(CHEMBL1823067)
Affinity DataIC50: 182nMAssay Description:Displacement of [3H]impiramine from human serotonin transporter membrane expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352702(CHEMBL1823067)
Affinity DataIC50: 1.37E+3nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed