BDBM50352607 CHEMBL1822138

SMILES Brc1csc(NC(=O)CN2C(=O)CCc3ncccc23)c1-c1nnc[nH]1

InChI Key InChIKey=JIQMILPCZGXYEY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50352607   

TargetMitogen-activated protein kinase 10(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50352607(CHEMBL1822138)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant JNK3 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50352607(CHEMBL1822138)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant JNK1 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50352607(CHEMBL1822138)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant JNK2 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50352607(CHEMBL1822138)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant p38alpha Thr69/71 of ATF-2 as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50352607(CHEMBL1822138)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant ERK2 using Ser383 of Elk-1 as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed