BDBM50352580 CHEMBL1825159::US8772288, 47

SMILES Cc1ccc(cc1-c1cnc2c(NC(=O)C22CCOCC2)c1)C(=O)NC1CC1

InChI Key InChIKey=PMWBLCWHEYJAND-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50352580   

TargetMitogen-activated protein kinase 14(Human)
Almirall

US Patent
LigandPNGBDBM50352580(CHEMBL1825159 | US8772288, 47)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 14(Human)
Almirall

US Patent
LigandPNGBDBM50352580(CHEMBL1825159 | US8772288, 47)
Affinity DataIC50: 13nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Almirall

US Patent
LigandPNGBDBM50352580(CHEMBL1825159 | US8772288, 47)
Affinity DataIC50: 86nMAssay Description:Inhibition of p38alpha in human whole blood assessed as reduction in TNF-alpha production by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed