BDBM50352576 CHEMBL1825156::US8772288, 43

SMILES Cc1ccc(cc1-c1ccc2c(NC(=O)C22CCCC2)n1)C(=O)NC1CC1

InChI Key InChIKey=QQOGVBYJBNUFEK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50352576   

TargetMitogen-activated protein kinase 14(Human)
Almirall

US Patent
LigandPNGBDBM50352576(CHEMBL1825156 | US8772288, 43)
Affinity DataIC50: 5.60nMpH: 7.5 T: 2°CAssay Description:Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 14(Human)
Almirall

US Patent
LigandPNGBDBM50352576(CHEMBL1825156 | US8772288, 43)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Almirall

US Patent
LigandPNGBDBM50352576(CHEMBL1825156 | US8772288, 43)
Affinity DataIC50: 128nMAssay Description:Inhibition of p38alpha in human whole blood assessed as reduction in TNF-alpha production by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed