BDBM50352575 CHEMBL1825160

SMILES Cc1ccc(cc1-c1cnc2c(NC(=O)C22CCC(F)(F)CC2)c1)C(=O)NC1CC1

InChI Key InChIKey=RXPMNVHJGHHMJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50352575   

TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352575(CHEMBL1825160)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352575(CHEMBL1825160)
Affinity DataIC50: 188nMAssay Description:Inhibition of p38alpha in human whole blood assessed as reduction in TNF-alpha production by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed