BDBM50352570 CHEMBL1825154

SMILES Cc1ccc(cc1-c1ccc2c(NC(=O)C22CCC(F)(F)CC2)c1)C(=O)Nc1ccon1

InChI Key InChIKey=IRPKJXGDXVWWFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50352570   

TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352570(CHEMBL1825154)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50352570(CHEMBL1825154)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of p38alpha in human whole blood assessed as reduction in TNF-alpha production by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed