BDBM50351968 CHEMBL1822390

SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)[C@H]1CCN(Cc2ccc(F)cc2)C[C@@H]1O

InChI Key InChIKey=UIWSYEZPNUYTKA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50351968   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50351968(CHEMBL1822390)
Affinity DataKi:  2.5nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in guinea pig brain membrane homogenates after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50351968(CHEMBL1822390)
Affinity DataKi:  294nMAssay Description:Displacement of (-)-[3H]vesamicol from human VAChT expressed in rat PC12 A123.7 cells after 20 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50351968(CHEMBL1822390)
Affinity DataKi:  1.49E+3nMAssay Description:Displacement of [125I]IABN from human dopamine D2 long receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50351968(CHEMBL1822390)
Affinity DataKi: >1.50E+4nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed