BDBM50351964 CHEMBL1822386

SMILES O[C@H]1CN(Cc2ccc(F)cc2)CC[C@@H]1N1CCC(CC1)C(=O)c1ccc(F)cc1

InChI Key InChIKey=MIOMZHKUIQMOIR-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50351964   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50351964(CHEMBL1822386)
Affinity DataKi:  0.480nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in guinea pig brain membrane homogenates after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50351964(CHEMBL1822386)
Affinity DataKi:  1.35E+3nMAssay Description:Displacement of [125I]IABN from human dopamine D2 long receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50351964(CHEMBL1822386)
Affinity DataKi:  1.36E+3nMAssay Description:Displacement of (-)-[3H]vesamicol from human VAChT expressed in rat PC12 A123.7 cells after 20 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50351964(CHEMBL1822386)
Affinity DataKi:  2.54E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50351964(CHEMBL1822386)
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed