BDBM50351945 CHEMBL1822046

SMILES CC(C)CCc1c(OCCCCCCC(=O)NO)ccc2ccc(=O)oc12

InChI Key InChIKey=KEVRYVQWWIUOTN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50351945   

TargetHistone deacetylase 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50351945(CHEMBL1822046)
Affinity DataIC50: 32.3nMAssay Description:Inhibition of HDAC1 using KI-177 as substrate incubated 30 mins before substrate addition measured after 30 mins post substrate addition by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50351945(CHEMBL1822046)
Affinity DataIC50: 553nMAssay Description:Inhibition of human HDAC8 using Boc-Lys(TFA)-AMC as substrate incubated 30 mins before substrate addition measured after 30 mins post substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50351945(CHEMBL1822046)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC4 using Boc-Lys(TFA)-AMC as substrate incubated 30 mins before substrate addition measured after 30 mins post substrate addition by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50351945(CHEMBL1822046)
Affinity DataIC50: 15.2nMAssay Description:Inhibition of HDAC6 using Boc-Lys(Ac)-AMC as substrate incubated 30 mins before substrate addition measured after 30 mins post substrate addition by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed