BDBM50351817 CHEMBL1824437

SMILES Cc1cccc(n1)-c1c(cnn1CC(=O)Nc1cccc(c1)C#N)-c1ccc2nc(C)c(C)nc2c1

InChI Key InChIKey=ZYENJEUYHCXCAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50351817   

TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50351817(CHEMBL1824437)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in insect Sf9 cells using casein as substrate by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50351817(CHEMBL1824437)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as substrate by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed