BDBM50351769 CHEMBL1823497

SMILES CCCCCCCCCCC#Cc1cn([C@@H]2O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@@H]2O)c(=O)[nH]c1=O

InChI Key InChIKey=HZILVFYAMVIYHP-UHFFFAOYSA-L

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50351769   

TargetFlavin-dependent thymidylate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Katholieke Universiteit Leuven

Curated by ChEMBL
LigandPNGBDBM50351769(CHEMBL1823497)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis ThyX-mediated dTMP synthesis using [5-3H]dUMP as substrate after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetThymidylate synthase ThyA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Katholieke Universiteit Leuven

Curated by ChEMBL
LigandPNGBDBM50351769(CHEMBL1823497)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged ThyA-mediated dTMP synthesis expressed in BL21 (DE3) Escherichia coli RbCl cells after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed