BDBM50351485 CHEMBL1819603

SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)Nc2cccc(CC(O)=O)c2)Oc2ccccc12

InChI Key InChIKey=OZLBZTVVEQQRSA-UHFFFAOYSA-N

Data  8 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50351485   

TargetProstaglandin D2 receptor(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351485(CHEMBL1819603)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351485(CHEMBL1819603)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351485(CHEMBL1819603)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]PGD2 from mouse prostanoid DP receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351485(CHEMBL1819603)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351485(CHEMBL1819603)
Affinity DataKi:  520nMAssay Description:Displacement of [3H]PGE2 from mouse prostaglandin EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351485(CHEMBL1819603)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]PGE2 from mouse prostaglandin EP1 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351485(CHEMBL1819603)
Affinity DataKi:  6.40E+3nMAssay Description:Displacement of [3H]Iloprost from human prostanoid IP receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351485(CHEMBL1819603)
Affinity DataKi:  6.40E+3nMAssay Description:Displacement of [3H]Iloprost from human prostanoid IP receptor expressed in CHO cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351485(CHEMBL1819603)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse prostaglandin EP3alpha receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351485(CHEMBL1819603)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse prostaglandin EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed