BDBM50351393 CHEMBL1819083

SMILES CCC(CC)Nc1c2CCCc2nc2c(c(C)nn12)-c1ccc(OC(F)F)cc1Cl

InChI Key InChIKey=FGOBMMBNSOPRGB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50351393   

TargetCorticotropin-releasing factor receptor 1(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351393(CHEMBL1819083)
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]CRF from human corticotropin-releasing factor receptor 1 expressed in CHO-K1 cells after 2 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50351393(CHEMBL1819083)
Affinity DataEC50:  200nMAssay Description:Antagonist activity at human corticotropin-releasing factor receptor 1 expressed in CHO-K1 cells assessed as inhibition of CRF-induced cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed