BDBM50351096 ASCORBIC ACID

SMILES OC[C@H](O)[C@H]1OC(=O)C(=O)C1O

InChI Key InChIKey=KRGQEOSDQHTZMX-UHFFFAOYSA-N

Data  1 KI  8 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50351096   

TargetTyrosinase(Human)
Gansu College of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50351096(ASCORBIC ACID)
Affinity DataIC50: 3.25E+4nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetHyaluronate lyase(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50351096(ASCORBIC ACID)
Affinity DataIC50: 6.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae hyaluronidase after 1 hr by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Rat)
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50351096(ASCORBIC ACID)
Affinity DataIC50: 2.65E+4nMAssay Description:The compound was tested for inhibition of malt Alpha-amylase by Megazyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAlbumin(Bovine)
Csir-National Institute For Interdisciplinary Science and Technology

Curated by ChEMBL
LigandPNGBDBM50351096(ASCORBIC ACID)
Affinity DataIC50: 1.55E+5nMAssay Description:Antiglycation activity in bovine serum albumin assessed as inhibition of advanced glycated end product formation after 24 hrs in presence of alpha-D-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
University of Pretoria

Curated by ChEMBL
LigandPNGBDBM50351096(ASCORBIC ACID)
Affinity DataIC50: 1.44E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate pretreated for 5 mins followed by substrate addition measured over 30 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2020
Entry Details Article
PubMed
TargetCatalase(Rat)
Sri Venkateswara University

Curated by ChEMBL
LigandPNGBDBM50351096(ASCORBIC ACID)
Affinity DataEC50:  7.77E+3nMAssay Description:Inhibition of catalase in Wistar rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
University of Pretoria

Curated by ChEMBL
LigandPNGBDBM50351096(ASCORBIC ACID)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of mushroom tyrosinase using as L-DOPA substrate after 2 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
University of Pretoria

Curated by ChEMBL
LigandPNGBDBM50351096(ASCORBIC ACID)
Affinity DataIC50: 3.87E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate incubated for 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
University of Pretoria

Curated by ChEMBL
LigandPNGBDBM50351096(ASCORBIC ACID)
Affinity DataIC50: 3.87E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Rat)
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50351096(ASCORBIC ACID)
Affinity DataKi:  4.34E+4nMAssay Description:Inhibitory constant against Alpha-amylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed