BDBM50350910 CHEMBL1817964

SMILES COc1oc(\C=C\C(C)C\C=C\C(\C)=C\C(C)C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C(\C)=C\C)c(C)c(=O)c1C

InChI Key InChIKey=HUWRGLWOOQKCCY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50350910   

TargetEpidermal growth factor receptor(Human)
Pharmamar Sau

Curated by ChEMBL
LigandPNGBDBM50350910(CHEMBL1817964)
Affinity DataIC50: 160nMAssay Description:Inhibition of EGFR-induced AP1 activation in human HeLa cells preincubated for 1 hr prior to EGF stimulation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Pharmamar Sau

Curated by ChEMBL
LigandPNGBDBM50350910(CHEMBL1817964)
Affinity DataIC50: 60nMAssay Description:Inhibition of EGFR-induced HIF1alpha activation in human HeLa cells preincubated for 1 hr prior to EGF stimulation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Pharmamar Sau

Curated by ChEMBL
LigandPNGBDBM50350910(CHEMBL1817964)
Affinity DataIC50: 170nMAssay Description:Inhibition of EGFR-induced Beta-casein activation in human HeLa cells preincubated for 1 hr prior to EGF stimulation by luciferase reporter gene assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed