BDBM50350802 CHEMBL1819121

SMILES COc1cc2ncnc(N3CCCC(C3)c3ccccc3)c2cc1OC

InChI Key InChIKey=QQBQKXDOFNGQJS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50350802   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Pfizer

Curated by ChEMBL

LigandBDBM50350802(CHEMBL1819121)Copy SMILESCopy InChI

Affinity DataIC50: 146nMAssay Description:Inhibition of recombinant rat PDE10A expressed in Sf9 cells using [3H]cAMP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2012
Entry Details Article
Copy Entry DOIPubMed
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TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50350802(CHEMBL1819121)Copy SMILESCopy InChI

Affinity DataIC50: 8.5nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL