BDBM50350582 CHEMBL1812910

SMILES CC(C)Cn1c(CN)c(-c2ccccc2)c2cc(\C=C\C(N)=O)ccc2c1=O

InChI Key InChIKey=UMRSSKBWGUGDJF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50350582   

TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50350582(CHEMBL1812910)
Affinity DataIC50: 280nMAssay Description:Inhibition of human DPP4 isolated from human CaCo2 cells incubated for 15 mins using Gly-Pro-pNA.Tos substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50350582(CHEMBL1812910)
Affinity DataIC50: 270nMAssay Description:Inhibition of DPP4 in rat plasma incubated for 60 mins using H-lys-Ala-pNA.2HCl substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50350582(CHEMBL1812910)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of DPP4 in rat spleen incubated for 60 mins using H-lys-Ala-pNA.2HCl substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 1(Bovine)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50350582(CHEMBL1812910)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of bovine spleen cathepsin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed