BDBM50350510 CHEMBL1814815

SMILES CC(=O)NCCC[C@H](NC(=O)[C@H](CCCCNC(C)=S)NC(=O)[C@H](CCCNC(C)=O)NC(C)=O)C(N)=O

InChI Key InChIKey=NLKWCCCQTZUFSF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50350510   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Akron

Curated by ChEMBL
LigandPNGBDBM50350510(CHEMBL1814815)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human GST-tagged SIRT1 using H2NHK-AcK-LM-COOH as substrate assessed as enzymatic deacetylation product formation after 5 mins by HPLC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Akron

Curated by ChEMBL
LigandPNGBDBM50350510(CHEMBL1814815)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human full length SIRT2 using H2N-MPSD-AcK-TIGG-COOH as substrate assessed as enzymatic deacetylation product formation after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Akron

Curated by ChEMBL
LigandPNGBDBM50350510(CHEMBL1814815)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human SIRT3 (102-399) using H2N-KRLPKTRSG-AcK-VMRRLLRKII-COOH as substrate assessed as enzymatic deacetylation product formation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed