BDBM50350360 CHEMBL1813283

SMILES Cc1c(CC(O)=O)c2ccccc2n1C(=O)c1ccc(OC[C@@H]2COc3ccccc23)cc1C

InChI Key InChIKey=KNTITMXOUMRIPL-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50350360   

TargetProstaglandin D2 receptor(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50350360(CHEMBL1813283)
Affinity DataIC50: 72nMAssay Description:Antagonist activity at mouse DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced cAMP accumulation after 10 mins by enzyme immu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50350360(CHEMBL1813283)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50350360(CHEMBL1813283)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed