BDBM50350311 CHEMBL1812661
SMILES [NH3+][C@@H](CCCCB(O)O)C([O-])=O
InChI Key InChIKey=HFKKMXCOJQIYAH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 28 hits for monomerid = 50350311
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of human Arg IMore data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Inhibition of human Arginase I in human myeloid-derived suppressor cells using L-arginine as substrate assessed as L-ornithine product formation by m...More data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Binding affinity to human ARG2 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Binding affinity to human ARG1 assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of rat ARG1More data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of N-terminal hexa-histidine tagged thrombin-cleavable human arginase 1 expressed in Escherichia coli DE3 cells measured after 90 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of rat liver arginase using L-arginine as substrate incubated for 10 mins followed by substrate addition by scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of human Arg IIMore data for this Ligand-Target Pair
Affinity DataIC50: 311nMAssay Description:Inhibition of human recombinant ARG1 expressed in Escherichia coli using thioarginine as a substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity to human Arg1 at pH 8.5More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of rat Arg1 at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of recombinant human ARG1 expressed in CHO-K1 cells assessed as reduction in urea level incubated for 24 hrs by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of human arginase-2 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 311nMAssay Description:Inhibition of human arginase1 in presence of DNTB by thio ornithine generation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of human recombinant arginase 1 expressed in Escherichia coli BL21 (DE3) assessed as reduction in urea production using L-arginine as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human arginase 1 using L-arginine as substrate measured after 60 mins in presence of manganese chloride by o-phthaldialdehy...More data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity to wild type human Arg I using L-arginine as substrate by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of human Arg2 by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of human Arg1More data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding affinity to human arginase 1 using L-arginine as substrate by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.10E+4nMAssay Description:Binding affinity to Plasmodium falciparum arginaseMore data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity to human arginase 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of human arginase-1 assessed as L-arginine conversion to L-ornithine measured as urea level after 1 hr by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Inhibition of human Arg2 at pH 7.5More data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Binding affinity to human arginase 2More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of N-terminal hexa-histidine tagged thrombin-cleavable rat arginase 1 expressed in Escherichia coli DE3 cells measured after 90 mins by co...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum arginase using L-arginine as substrate by colorimetric assayMore data for this Ligand-Target Pair