BDBM50350309 CHEMBL1812662

SMILES CC([NH3+])(CCCCB(O)O)C([O-])=O

InChI Key InChIKey=VJCNFQNUKLFMMR-UHFFFAOYSA-N

Data  1 KI  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50350309   

TargetArginase-1(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50350309(CHEMBL1812662)
Affinity DataKd:  880nMAssay Description:Binding affinity to human arginase 1 using L-arginine as substrate by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetArginase-2, mitochondrial(Human)
Institutes For Pharmaceutical Discovery

Curated by ChEMBL
LigandPNGBDBM50350309(CHEMBL1812662)
Affinity DataIC50: 5.07E+3nMAssay Description:Inhibition of human Arg2 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetArginase-1(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50350309(CHEMBL1812662)
Affinity DataIC50: 3.43E+3nMAssay Description:Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetArginase-1(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50350309(CHEMBL1812662)
Affinity DataKd:  880nMAssay Description:Binding affinity to human Arg I assessed as inhibition constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetArginase(malaria parasite P. falciparum)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50350309(CHEMBL1812662)
Affinity DataKi:  2.60E+5nMAssay Description:Inhibition of Plasmodium falciparum arginase using L-arginine as substrate by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed