BDBM50350110 CHEMBL1814068

SMILES Clc1ccc(NC(=O)c2coc3ccccc3c2=O)cc1

InChI Key InChIKey=JNHOMPJUMGTTSC-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50350110   

TargetAmine oxidase [flavin-containing] B(Human)
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50350110(CHEMBL1814068)
Affinity DataIC50: 63nMAssay Description:Inhibition of human MAO-B assessed as inhibition of p-tyramine oxidation to p-hydroxyphenyl-acetaldehyde after 15 mins by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50350110(CHEMBL1814068)
Affinity DataIC50: 8nMAssay Description:Inhibition of human MAO-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50350110(CHEMBL1814068)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MAO-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50350110(CHEMBL1814068)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate by amplex red-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50350110(CHEMBL1814068)
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant MAOBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50350110(CHEMBL1814068)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50350110(CHEMBL1814068)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Universidade Do Porto

Curated by ChEMBL
LigandPNGBDBM50350110(CHEMBL1814068)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed