BDBM50349826 SYRINGARESINOL

SMILES COc1cc(cc(OC)c1O)[C@H]1OC[C@H]2[C@@H]1CO[C@@H]2c1cc(OC)c(O)c(OC)c1

InChI Key InChIKey=KOWMJRJXZMEZLD-UHFFFAOYSA-N

Data  3 IC50  2 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50349826   

TargetForkhead box protein O3(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50349826(SYRINGARESINOL)
Affinity DataKd:  1.73E+6nMAssay Description:Binding affinity to His-tagged FOXO3a (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50349826(SYRINGARESINOL)
Affinity DataEC50:  1.81E+4nMAssay Description:Activation of PPARbeta-LBD (unknown origin) assessed as fluorescein-labeled coactivator C33 recruitment by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50349826(SYRINGARESINOL)
Affinity DataKd:  2.76E+4nMAssay Description:Binding affinity to recombinant PPARbeta-LBD (254 to 441 residues) (unknown origin) expressed in Escherichia coli Rosetta2 cells by isothermal titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Institute of Medicinal Plant Development

Curated by ChEMBL
LigandPNGBDBM50349826(SYRINGARESINOL)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA after 10 mins by ELISA readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50349826(SYRINGARESINOL)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of PTP1B (unknown origin) assessed as p-nitrophenol release from pNPP substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50349826(SYRINGARESINOL)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed