BDBM50349760 CHEMBL1809187::US8822447, 38

SMILES CCc1nn(-c2ccccc2)c2cc(NC(=O)c3ccc4nc[nH]c4c3)ccc12

InChI Key InChIKey=YCMJMIYGGKQKMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50349760   

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349760(CHEMBL1809187 | US8822447, 38)
Affinity DataIC50: 940nMT: 2°CAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349760(CHEMBL1809187 | US8822447, 38)
Affinity DataIC50: 940nMAssay Description:Inhibition of KHK-mediated conversion of D-fructose to fructose-1-phosphate after 60 mins by high throughput mass spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed