BDBM50349680 CHEMBL1809013

SMILES O[C@@H]1CCN(C1)C(=O)[C@H]1CN([C@@H]2Cc3c[nH]c4cccc(C2=C1)c34)C(=O)Nc1ccccc1

InChI Key InChIKey=YGQOORWVQMHJON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50349680   

TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50349680BDBM50349680(CHEMBL1809013)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human CXCR3 expressed in mouse L1.2 cells assessed as inhibition of ITAC-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50349680BDBM50349680(CHEMBL1809013)
Affinity DataIC50: 61nMAssay Description:Displacement of radiolabeled CXCL11 from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed