BDBM50349608 CHEMBL1808948

SMILES CCOC(=O)CN(Cc1ccc(F)cc1)c1ccc2OC(C)(COc3ccc(cc3)C(N)=N)CN(C)c2c1

InChI Key InChIKey=WWYBLKJQTZEQJI-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50349608   

TargetIntegrin alpha-IIb/beta-3(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50349608(CHEMBL1808948)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of biotinylated fibrinogen from human alpha2b-beta3 receptor after 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50349608(CHEMBL1808948)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of biotinylated fibrinogen from human alpha5-beta3 receptor after 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50349608(CHEMBL1808948)
Affinity DataKi:  690nMAssay Description:Inhibition of thrombin using S-2238 as substrate after 15 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50349608(CHEMBL1808948)
Affinity DataKi:  720nMAssay Description:Inhibition of thrombin using S-2238 as substrate preincubated for 15 mins prior substrate addition measured for every 10 secs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50349608(CHEMBL1808948)
Affinity DataKi:  6.66E+3nMAssay Description:Inhibition of factor 10a using S-2222 as substrate preincubated for 15 mins prior substrate addition measured for every 10 secs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed