BDBM50349572 CHEMBL1808867

SMILES Clc1cccc(c1)-c1ccc(cn1)C1CCCN1C(=O)c1nccs1

InChI Key InChIKey=ZDRLSVCSTYWGGZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50349572   

TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50349572(CHEMBL1808867)
Affinity DataIC50: 5nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50349572(CHEMBL1808867)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]-MPEP from human mGluR5 expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed