BDBM50349551 CHEMBL1808894

SMILES Cc1cc(ccn1)-c1cc(C)c(cn1)C1CCCN1C(=O)c1cncs1

InChI Key InChIKey=UNOLYCWUAKOIGH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50349551   

TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50349551(CHEMBL1808894)
Affinity DataIC50: 120nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50349551(CHEMBL1808894)
Affinity DataKi:  840nMAssay Description:Displacement of [3H]-MPEP from human mGluR5 expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed