BDBM503491 4-Chloro-1-ethyl-N-(((1r,4R)-1-hydroxy-4-(methylsulfonyl)cyclohexyl)methyl)-5-(4-methoxy-6-(((R)-1,1,1-trifluoropropan-2-yl)oxy)pyridin-3-yl)-1H-pyrazole-3-carboxamide::US11034658, Example 63

SMILES CCn1nc(C(=O)NC[C@@]2(O)CC[C@H](C)CC2)c(Cl)c1-c1cnc(O[C@H](C)C(F)(F)F)cc1OC

InChI Key InChIKey=HSFFEENVZVQWEF-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503491   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM503491(4-Chloro-1-ethyl-N-(((1r,4R)-1-hydroxy-4-(methylsu...)
Affinity DataKd:  12nMAssay Description:ThermoFluor is a fluorescence based assay that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal stability (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent