BDBM50348721 CHEMBL1801490

SMILES CC(C)Cc1nc2ccccc2n1Cc1cc(=O)[nH]c2c(F)c(F)ccc12

InChI Key InChIKey=KPIBTYOXTSLBPM-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50348721   

TargetNitric oxide synthase, endothelial(Human)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50348721(CHEMBL1801490)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human eNOS expressed in HEK293 cells assessed as inhibition A23187 induced nitric oxide production incubated for 24 hrs measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50348721(CHEMBL1801490)
Affinity DataEC50:  380nMAssay Description:Inhibition of human iNOS expressed in HEK293 cells assessed as inhibition of nitric oxide production after 18 hrs using 2,3-diaminonaphthalene by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50348721(CHEMBL1801490)
Affinity DataEC50:  690nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50348721(CHEMBL1801490)
Affinity DataEC50:  3.10E+3nMAssay Description:Inhibition of mouse iNOS expressed in HEK293 cells assessed as inhibition of nitric oxide production after 18 hrs using 2,3-diaminonaphthalene by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed