BDBM50347956 CHEMBL1800143::US8637558, 32

SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCC2CCCCC2)c(Cl)c1

InChI Key InChIKey=PWMWQEDMHMQOSU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50347956   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Industry-Academic Cooperation Foundation, Chosun University

US Patent
LigandPNGBDBM50347956(CHEMBL1800143 | US8637558, 32)
Affinity DataIC50: 10.3nMpH: 7.5Assay Description:Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Industry-Academic Cooperation Foundation, Chosun University

US Patent
LigandPNGBDBM50347956(CHEMBL1800143 | US8637558, 32)
Affinity DataIC50: 10nMAssay Description:Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed