BDBM50347806 CHEMBL1802401

SMILES Nc1nccc(n1)-c1c[nH]c2c(cccc12)[N+]([O-])=O

InChI Key InChIKey=SYRGMMJIEWOFNF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50347806   

TargetDual specificity protein kinase CLK1(Human)
Clermont Universite£

Curated by ChEMBL
LigandPNGBDBM50347806(CHEMBL1802401)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50347806(CHEMBL1802401)
Affinity DataIC50: 85nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A using myelin protein as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Clermont Universite£

Curated by ChEMBL
LigandPNGBDBM50347806(CHEMBL1802401)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human recombinant CDK5/p25 using Histone H1 and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50347806(CHEMBL1802401)
Affinity DataIC50: 9.95E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged GSK3B recombinant in baculovirus expression system using Alexa-Fluor tracer-236 incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed