BDBM50347384 CHEMBL1801238

SMILES ONC(=O)c1cnc(nc1)N1C[C@H]2[C@@H](C1)[C@@H]2NCc1ccc(Cl)cc1

InChI Key InChIKey=AQIOMPMNFDEIJO-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50347384   

TargetHistone deacetylase 5(Human)
Chroma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50347384(CHEMBL1801238)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant HDAC5 using fluor de Lys as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Chroma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50347384(CHEMBL1801238)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant HDAC1 using fluor de Lys as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Chroma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50347384(CHEMBL1801238)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Chroma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50347384(CHEMBL1801238)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Chroma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50347384(CHEMBL1801238)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Chroma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50347384(CHEMBL1801238)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human recombinant HDAC6 using fluor de Lys as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Chroma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50347384(CHEMBL1801238)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant HDAC3 using fluor de Lys as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Chroma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50347384(CHEMBL1801238)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant HDAC2 using fluor de Lys as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed